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Abstract
Introduction: Maintaining adequate blood supplies remains a persistent challenge, particularly in tourist cities such as Guarujá, where seasonal population variation affects donation rates. High ineligibility rates during clinical and serological screening compromise blood availability and highlight the importance of educational actions for safe donation. Objective: To analyze the profile of blood donation candidates and identify the main causes of ineligibility at the Santo Amaro Hospital Blood Bank, Guarujá-SP, from 2021 to 2024. Methodology: A retrospective cross-sectional quantitative study was conducted using documental data from the hemotherapy service. Demographic characteristics, donation type, donor frequency, and clinical and serological causes of rejection were evaluated. Results: From 2021 to 2024, male donors predominated (59%), with an average 19% reduction between clinical and serological screening. The main clinical causes of ineligibility were anemia and risk behavior. In laboratory screening, syphilis and hepatitis were the leading causes. The pattern remained consistent across the years, revealing low replacement donation rates and direct impact on the local blood supply. Conclusion: The findings emphasize the urgent need for educational campaigns to minimize risk behaviors and increase the number of eligible donors, especially during high tourist influx periods. Strengthening information strategies on donation criteria and STI prevention is essential for maintaining regional hemotherapy stability.
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