Use of Lactobionic Acid in Photoaged Skin
Article Sidebar
Main Article Content
Abstract
Various cosmetic formulations use actives to attenuate the signs of photoaging, substances such as alpha hydroxy acids, beta hydroxy acids and polyhydroxy acids. This literature review discusses the molecular aspects of polyhydroxy acid lactobionic acid and its effects on photoaged skin, according to some clinical data were observed fine lines and wrinkles around the eyes, flaccidity, dilated ostia, roughness and luminosity on the face. In its histology the effects of UV radiation on skin changes. As a result, lactobionic acid has been shown to be effective in improving clinical signs of photoaged skin.
Keywords: Photoaging, Free radical, metalloproteinase, Lactobionic acid.
Article Details
Copyright Statement - Policy Proposal for Open Access Journals
Authors who publish in the Brazilian Journal of Natural Sciences (BJNS) agree to the following terms: 1 - Authors retain the copyright and grant the journal the right to first publication, with the work simultaneously licensed under the Creative Commons Attribution License allowing sharing of the work with recognition of the authorship of the work and initial publication in this journal. 2 - Authors are authorized to assume additional contracts separately, for non-exclusive distribution of the version of the work published in this journal (eg, publishing in institutional repository or as a book chapter), with acknowledgment of authorship and initial publication in this journal. 3 - Authors are allowed and encouraged to publish and distribute their work online (eg in institutional repositories or on their personal page) at any point before or during the editorial process, as this can generate productive changes, as well as increase the impact and citation of published work. This is an open access article under the CC-BY license
(http://creativecommons.org/licenses/by/4.0)
References
[2] Fandos, L.S. Alta Cosmética II Objetivos e Protocolos de Tratamentos, 1ed.,Buenos Aires: O Autor, 2005. p.22-24.
[3] Harris, M.I.N.C.; Pele-Estrutura, Propriedades e Envelhecimento. 3ed; São Paulo:Senac;2003:218-220.
[4] Orringer JS, Johnson TM, Kang S, Karimipour DJ, Hammerberg C, Hamilton T, et al. Effect of carbon Dioxide P53 imonunostaining in photodamaged skin. Arch Dermatol. 2004 Sep;140(9):1073-7.
[5] Bruckner-Tuderman L.;Biology of the extracellular matrix, In: Bolognia JL, Jorizzo JL, Rapini RP, editors. Dermatology. 1 ed. London: Mosby:2003. p. 1483-96.
[6] Mcgrath JA, Eady RAJ, Pope FM. Anatomy and Organization of human skin. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rooks, Textbook of Dermatology. 7th ed. Oxford: Blackwell Publishing;2005. p.3.1-84.
[7] Kede, Maria P.V.; Sabatovich, O. Dermatologia Estética, 2ed. revisada e ampliada – São Paulo: Editora Atheneu; 2009: 387-395.
[8] Chebassier N, El Houssein O, Viegas I, Dreno B.;In vitro induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 expression in Keratinocytes by boron and manganese. Exp Dermatol 2004; 13(8):484-90.
[9] Green BA, Edison BL, Wildnauer RH, et al.;Lactobionic Acid and gluconolactone: PHas for photoaged skin. Cosmetic Dermatology 2001;14(9):24-28.
[10] Maio M.; Tratado de Medicina Estetica, 1ͣ ed., São Paulo: Roca, 2004, p.299-301.
[11] Nardin, P.;Guterres, S.S.; Alfa-Hidroxiácidos: Aplicações cosméticas e dermatológicas, Caderno de Farmácia, 1999,v.15, n.1, p.7-14. Disponível em
[13] Ribeiro, C.J., Cosmetologia Aplicada a Dermoestética.2ed; São Paulo: Pharmabooks; 2010:261-263.
[14] O’Neil MJ, Smith A, Helkelman PE, et al, eds. The Merck Index, 13th ed. Whitehouse Station, KJ: Merck &Co;2001:5354.
[15] Green B, Tseng C, Wildnauer R, et al.;Safety and efficacy of a gluconolactose (polyhydroxy acid) containing regimen on sensitive skin and photodamage following controlled consumer use. Poster presented at: American Academy of Dermatology Annual Meeting: March, 1999; San Francisco, CA.
[16] Southard JH, Belzer FO. Organ preservation. Annu Rev Med 1995;46:235-247.
[17] Barquet, A.P.; Funck, A.P.; Koester, L.S. Comparação entre alfa hidroxiácidos e polihidroxiácidos na cosmiatria e dermatologia. Revista Brasileira Farmacêutica, 87, 3,67-73, 2006.
[18] Yu Rj, Van Scott EJ. α – hydroxyacids, polyhydroxy acids, aldobionics acids and their topical actions. In: Baran R, Maibach HI, eds. Textbook of cosmetic dermatology, 3rd edn. New York: Taylor & Francis: 2005 pp.77-93.
[19 Upadhya GA, Strasberg SM.; Glutathione, lactobione and histidine: cryptic inhibitors of matrix metalloproteinases contain. Ed in University of Wisconsin and histidine tryptophan/ketoglutarate liver preservation solution. Hepatology 2000:31:1115-22.
[20] Green B, RPh, MS, Brenda L, Edison BL, Monya L.;Antiaging Effects of Topical Lactobionic Acid: Results of a controlled usage study. Cosmetic Dermatology 2008;21(2):1-7.
[21]Krutmann J. The role of UVA rays in skin aging. Eur J Dermatol. 2001;11:170-1
[22] Hernandez-Pigeon H, Jean C, Charruyer A, Haure MJ, Baudouin C, Charveron M, et al. UVA induces granzyme B in human keratinocytes through MIF: implication in extracellular matrix remodeling. J Biol Chem.2007;282:8157-64.